{"id":4066,"date":"2020-06-12T17:05:42","date_gmt":"2020-06-12T15:05:42","guid":{"rendered":"https:\/\/cuidsalud.com\/?post_type=portfolio&p=4066"},"modified":"2022-06-21T21:06:45","modified_gmt":"2022-06-21T19:06:45","slug":"study-reox","status":"publish","type":"portfolio","link":"https:\/\/cuidsalud.com\/en\/portfolio\/study-reox\/","title":{"rendered":"The REOX study"},"content":{"rendered":"

Antioxidant dressing therapy versus standard wound care in chronic wounds (the REOX study)<\/strong><\/span> \"\" Chronic wounds are a major clinical and economic problem for health care institutions because of their impact on the quality of life of both patients and caregivers. Wound healing is impaired when the wound remains in the inflammatory stage for too long. A range of factors that can delay the healing process have been described, and include the imbalance between proteases and protease inhibitors in the wound bed, bacterial colonization and the presence of biofilm, and oxidative stress.<\/span> This project focus in an antioxidant dressing (Reoxcare<\/a>\u00ae) that was developed by Histocell (Bizkaia, Spain). The components of this dressing act as free radical scavengers since two of them also have a synergistic antioxidant effect. Due to the innovative design, this antioxidant dressing combines the advantages of moist healing in exudate management and free radical neutralization, achieving wound reactivation.<\/span> This dressing with antioxidant properties has been tested in animal models and in case series of patients with acute wounds and chronic wounds of various aetiologies showing favourable results in activating the healing process.<\/span> However, there is currently no study comparing this new antioxidant dressing with standard wound dressings that maintain a moist environment that are used in routine clinical practice for the treatment of chronic wounds. This trial aims to fill this gap in the knowledge.<\/span><\/p>\n

Objectives<\/span><\/strong><\/p>\n

The primary aim of this study is to compare the effect of an antioxidant dressing on the healing of chronic wounds against the use of dressings that create a moist environment (as standard clinical practice) in patients with hard-to-heal wounds.<\/span> The secondary aims are to measure the intrapatient variation over time in the percentage of nonviable and granulation tissue in the wound bed and to measure the reduction in the wound area.<\/span><\/p>\n

Research team<\/span><\/strong><\/p>\n